Risk-Informed Data Analytics for Sustainable Pharmaceutical Supply: A Governance Framework for Public Oncology Hospitals

Unofficial AI-generated summary based on the public title and abstract. Not an official translation.

🔬研究者:Provides a novel integration of ABC-XYZ analysis with environmental impact assessment in healthcare supply chain, with Monte Carlo validation.

🏢実務担当者:Offers actionable inventory policy adjustments that reduce stockouts, urgent orders, and carbon footprint, directly applicable to hospital pharmacy management.

🏛政策担当者:Highlights how data-driven governance can align public health procurement with climate goals, relevant for health ministry sustainability strategies.

Ensuring uninterrupted access to essential medicines in public healthcare systems is a persistent challenge with clinical, economic, and environmental implications. Oncology services are particularly vulnerable to stockouts, which compromise therapeutic continuity and increase reliance on urgent procurement with high carbon and waste footprints. This study proposes a risk-informed, data-driven framework for pharmaceutical inventory governance in a high-complexity public oncology hospital in Chile, aligning with sustainability goals and green supply chain principles. Using operational data from 2023–2024, we integrate descriptive analytics, ABC–XYZ segmentation, and a continuous-review (s, Q) policy extended through a Logistic Risk Index (LRI) that consolidates demand variability, supply performance, and clinical-economic criticality. Empirical analysis reveals strong expenditure concentration in AX/AY segments and significant misalignment between institutional and analytically derived parameters. A Monte Carlo simulation N = 1000 runs per scenario) compares baseline, adjusted, and fully risk-informed policies under stochastic demand and lead-time conditions. Results show that the risk-informed configuration reduces stockout exposure by up to 46%, improves fill rates (93.1% → 96.4%), and shortens replenishment delays, while maintaining total logistic cost stability. Critically, urgent orders decrease from 27.4 to 14.8 per year, avoiding an estimated 630 kg CO2 emissions and 25 kg of packaging waste annually. These findings demonstrate that resilience, efficiency, and sustainability are not competing objectives but can be jointly achieved through integrated analytics and governance. The proposed approach offers a scalable blueprint for public health systems seeking to transition from reactive inventory management toward anticipatory, transparent, and sustainability-oriented decision-making, contributing to SDG 3 (health and well-being) and SDG 12 (responsible consumption and production).

• semanticscholar https://doi.org/10.3390/systems14040358first seen 2026-05-05 22:09:14