Greenhouse gas emissions of sevoflurane outweigh those of carrier gas and CO2 absorbers across the fresh gas flow spectrum
セボフルランの温室効果ガス排出量は、新鮮ガス流量スペクトル全体でキャリアガスおよびCO2吸収剤の排出量を上回る (AI 翻訳)
Jennifer Jouwena, Andre M. De Wolf, Thomas J. Hendrickx, Jan F.A. Hendrickx
🤖 gxceed AI 要約
日本語
セボフルラン麻酔における温室効果ガス排出量を定量化。新鮮ガス流量（FGF）の低下がセボフルランのCO2e排出削減に最も効果的であり、キャリアガスやCO2吸収材の寄与は3%未満であることを示した。
English
This study quantifies the CO2 equivalent emissions of sevoflurane anesthesia across fresh gas flows. Sevoflurane emissions dominate (>97% of total), and lowering fresh gas flow is the key to reducing global warming impact.
Unofficial AI-generated summary based on the public title and abstract. Not an official translation.
📝 gxceed 編集解説 — Why this matters
日本のGX文脈において
日本では医療分野の脱炭素化が進んでおらず、本論文は手術室での具体的な排出削減策（低流量麻酔）を定量的に示す点で参考になる。ただし、日本の麻酔診療報酬や環境規制との連携は今後の課題。
In the global GX context
This paper provides granular data on anesthetic gas emissions, relevant for healthcare decarbonization globally. It highlights that reducing fresh gas flow is more impactful than changing absorbents or carrier gases, which can inform hospital procurement and clinical guidelines.
👥 読者別の含意
🔬研究者:Provides a detailed emission breakdown for sevoflurane, useful for life-cycle analysis of medical gases.
🏢実務担当者:Hospitals can use these data to prioritize low-flow anesthesia protocols as a carbon reduction measure.
🏛政策担当者:Could inform healthcare carbon accounting standards or procurement policies for anesthetic agents.
📄 Abstract（原文）
Background: The absolute and relative effects of lowering fresh gas flows (FGF) on the CO 2 equivalent (CO 2 e) emissions of sevoflurane, carrier gases (O 2 /air) and prepacked CO 2 canister remain poorly quantified. We quantified these factors across a 0.2-4 L/min FGF range during the first hour of anesthesia. Methods: Data were compiled from 3 studies including 132 ASA I-III patients receiving a constant end-tidal sevoflurane concentration (FETsevo) using manual (n = 50) or target controlled delivery (n = 48) with 0.2 to 4 L/min FGF or during automated closed-circuit delivery (CCA) (n=34). Sevoflurane consumption was normalized to both 1.3 and 2.0% FETsevo, and carrier gas use to an inspired O 2 concentration (F I O 2 ) of 30 and 60%. Prepacked CO 2 absorbent usage was calculated using a previously described model for both 130 and 160 mL/min exhaled CO 2 (VCO 2 ). Published CO 2 e values were used to derive CO 2 e of sevoflurane. Results: Sevoflurane CO 2 e increases linearly with FGF (range 2.4 -18.6 kg CO 2 e), except when a brief wash-in period was used due to low FGF (FGF < 1 L/min). Carrier gas CO 2 e decreases with lower FGF but in a more complex manner, and increases with higher F I O 2 . (range 0.010 - 0.124 kg CO 2 e). Absorbent CO 2 e decreases linearly with FGF (range 0 - 0.070 kg CO 2 e). The CO 2 e of sevoflurane is two orders of magnitude higher than CO 2 e of carrier gas and CO 2 absorbent, which are similar. Conclusions: When delivering sevoflurane in O 2 /air, the CO 2 e contribution of the carrier gas and CO 2 absorbent is less than 3%, even during CCA. While CO 2 e is only one element of a comprehensive life cycle analysis, the presented CO 2 e data underscore that the key to minimizing the global warming potential of sevoflurane is lowering FGF and decreasing FETsevo.
🔗 Provenance — このレコードを発見したソース
- crossref https://doi.org/10.1097/aln.0000000000006238first seen 2026-07-17 06:14:17
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